{"title":"14914-MASP-2","description":"","products":[{"product_id":"masp-2-human-elisa-kit-1-x-96-det","title":"MASP-2, Human, ELISA kit, 1 x 96 det.","description":"\u003cul\u003e\n\u003cli\u003eMASP-2 is a MBL associated serine protease. Mannan-binding lectin (MBL) and ficolins, in complex with MASPs, are capable of activating the complement system, thus mediating the destruction of infectious agents. After oligomerisation of MBL (or L-Ficolin) MASP-2 will be bound and activated. Activated MASP-2 cleaves C4 and C2 and is crucial for the activation of downstream complement components. MASP-2 deficiency will result in an increased susceptibility for infections (e.g. leukemia patients in chemotherapy are at high risk of serious infections). Even more so then MBL deficiency, because MASP-2 is also required for complement activation by H- and L-ficolin. The ELISA detects MASP-2 in serum and plasma. The MASP-2 levels in plasma from healthy individuals range from 170 to 1196 ng\/ml.\u003c\/li\u003e\n\u003cli\u003eThe human MASP-2 ELISA has been developed for the quantitative measurement of natural human MASP-2 in cell culture medium, plasma and serum.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614113259811,"sku":"HYBHK32601","price":1493.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_9d7d877d-8424-486b-8712-7b6679bb56b2.png?v=1753030310"},{"product_id":"masp-2-human-elisa-kit-2-x-96-det","title":"MASP-2, Human, ELISA kit, 2 x 96 det.","description":"\u003cul\u003e\n\u003cli\u003eMASP-2 is a MBL associated serine protease. Mannan-binding lectin (MBL) and ficolins, in complex with MASPs, are capable of activating the complement system, thus mediating the destruction of infectious agents. After oligomerisation of MBL (or L-Ficolin) MASP-2 will be bound and activated. Activated MASP-2 cleaves C4 and C2 and is crucial for the activation of downstream complement components. MASP-2 deficiency will result in an increased susceptibility for infections (e.g. leukemia patients in chemotherapy are at high risk of serious infections). Even more so then MBL deficiency, because MASP-2 is also required for complement activation by H- and L-ficolin. The ELISA detects MASP-2 in serum and plasma. The MASP-2 levels in plasma from healthy individuals range from 170 to 1196 ng\/ml.\u003c\/li\u003e\n\u003cli\u003eThe human MASP-2 ELISA has been developed for the quantitative measurement of natural human MASP-2 in cell culture medium, plasma and serum.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614113325347,"sku":"HYBHK32602","price":2411.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_a02a41cc-f308-4ba3-985d-9d53df7146cb.png?v=1753030313"}],"url":"https:\/\/chromspec.com\/collections\/14914-masp-2.oembed","provider":"Chromatographic Specialties Inc.","version":"1.0","type":"link"}