{"title":"14961-Antibody Name D","description":"","products":[{"product_id":"dermcidin-human-mab-g-81-200-ug","title":"Dermcidin, Human, mAb G-81, \u003e200 µg","description":null,"brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614135771427,"sku":"HYBHM2040200UG","price":561.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_18ee34b0-fd8c-48fe-86b1-5db139ece688.png?v=1753031265"},{"product_id":"defensin-5-human-mab-8c8","title":"Defensin 5, Human, mAb 8C8","description":"\u003cul\u003e\n\u003cli\u003eThe monoclonal antibody 8C8 recognizes human alpha-defensin 5 (HD5). HD5 is an antimicrobial peptide produced by Paneth cells, specialized epithelial cells of the small intestinal crypt. HD5 is stored in the Paneth cells as propeptide (aa 20-94) and released as mature peptide after trypsin digestion, which is co-secreted from the Paneth cell granules. The mature HD5 (aa 63-94) is protected from further digestion by the proteolysis enzyme. HD5 functions in maintaining the correct microbial balance in the intestine. Transgenic mice that express HD5 are protected from lethal challenge caused by Salmonella typhimurium. Expression levels of HD5 are negatively correlated to intestinal infection. HD5 is a useful marker for intestinal metaplasia of the upper gastrointestinal tract. HD5 expression has also been detected in the upper half of the stratified squamous epithelium of the vagina and ectocervix with increasing intensity toward the lumen. Secreted HD5 is detectable in cervicovaginal lavages, with highest concentrations during the secretory phase of the menstrual cycle. The monoclonal antibody 8C8 was raised against recombinant HD5 (aa 20-94) and recognizes the propeptide and the partially processed forms (aa 36-94 and 56-94), but it hardly recognizes mature peptide. No cross reactivity with HD6, lysozyme, or sPLA2 could be detected.\u003c\/li\u003e\n\u003cli\u003eApplications: Frozen sections, Immunoassays , Western Blot\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614150811939,"sku":"HYBHM2228100UG","price":990.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_15b5ed20-31cc-41a1-aadb-585cc255e867.png?v=1753031807"},{"product_id":"defensin-5-human-mab-8c8-20-ug","title":"Defensin 5, Human, mAb 8C8, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614150844707,"sku":"HYBHM222820UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_ccaad8bf-09af-4211-bdd3-0cdcc86780d7.png?v=1753031810"},{"product_id":"defensin-5-human-mab-8c8-500-ug","title":"Defensin 5, Human, mAb 8C8, 500 µg","description":null,"brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614150877475,"sku":"HYBHM2228500UG","price":2080.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_e6fe53e3-a68e-4edf-a9e8-7c50422a1208.png?v=1753031813"},{"product_id":"daf-human-mab-1c6","title":"DAF, Human, mAb 1C6","description":"\u003cul\u003e\u003cli\u003eThe monoclonal antibody 1C6 recognizes human complement decay-accelerating factor (DAF), also designated as CD55. Cells express on their surface several proteins which protect against complement attack, namely complement receptor I (CR1), decay-accelerating factor (DAF), membrane cofactor protein (MCP) and CD59. CR1, DAF and MCP regulate the activation pathways of complement by either accelerating decay of the C3 and C5 convertase (CR1, DAF), or acting as cofactors for the serine protease factor I, which cleaves and irreversibly inactivates C3b (CR1, MCP).\u003c\/li\u003e\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614153138467,"sku":"HYBHM2280100UG","price":799.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_f7a7cdbe-3b05-4882-8e11-fa149caf8515.png?v=1753031876"},{"product_id":"daf-human-mab-1c6-20-ug","title":"DAF, Human, mAb 1C6, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614153171235,"sku":"HYBHM228020UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_988877f0-c8c3-494e-858a-c40a703b7173.png?v=1753031880"}],"url":"https:\/\/chromspec.com\/collections\/14961-antibody-name-d.oembed","provider":"Chromatographic Specialties Inc.","version":"1.0","type":"link"}