{"title":"14965-Antibody Name F","description":"","products":[{"product_id":"ficolin-3-human-mab-4h5","title":"Ficolin-3, Human, mAb 4H5","description":"\u003cul\u003e\u003cli\u003eThe monoclonal antibody 4H5 recognizes human Ficolin-3, also known as H-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation.\u003c\/li\u003e\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139441443,"sku":"HYBHM2089100UG","price":990.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_592c6144-1795-4356-ba63-4ebf30552fcd.png?v=1753031432"},{"product_id":"ficolin-3-human-mab-4h5-20-ug","title":"Ficolin-3, Human, mAb 4H5, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139474211,"sku":"HYBHM208920UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_5ea35a6f-77a5-4ea6-983a-2b0816a74a60.png?v=1753031435"},{"product_id":"ficolin-2-human-mab-gn4","title":"Ficolin-2, Human, mAb GN4","description":"\u003cul\u003e\u003cli\u003eThe monoclonal antibody GN4 recognizes human Ficolin-2, also known as L-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation.\u003c\/li\u003e\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139506979,"sku":"HYBHM2090100UG","price":990.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_8f5675c2-0ecd-4da9-a09e-3225c0bc1e15.png?v=1753031439"},{"product_id":"ficolin-2-human-mab-gn4-20-ug","title":"Ficolin-2, Human, mAb GN4, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139539747,"sku":"HYBHM209020UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_51b5e06e-9ecb-4898-8e5e-e52e4ef32118.png?v=1753031442"},{"product_id":"ficolin-2-human-mab-gn5","title":"Ficolin-2, Human, mAb GN5","description":"\u003cul\u003e\u003cli\u003eThe monoclonal antibody GN5 recognizes human Ficolin-2, also known as L-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation.\u003c\/li\u003e\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139605283,"sku":"HYBHM2091100UG","price":990.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_c752ae1d-846e-408a-a3e6-96588aec1a9d.png?v=1753031447"},{"product_id":"ficolin-2-human-mab-gn5-20-ug","title":"Ficolin-2, Human, mAb GN5, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139638051,"sku":"HYBHM209120UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_43e812de-a5bf-4002-b777-c489f79e15eb.png?v=1753031451"},{"product_id":"ficolin-2-human-mab-gn5-500-ug","title":"Ficolin-2, Human, mAb GN5, 500 µg","description":null,"brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139670819,"sku":"HYBHM2091500UG","price":2080.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_42f08644-73bf-4070-892f-aa4a769083db.png?v=1753031454"},{"product_id":"fhl2-human-mab-f4b2-b11","title":"FHL2, Human, mAb F4B2-B11","description":"\u003cul\u003e\n\u003cli\u003eThe monoclonal antibody F4B2-B11 reacts specifically with the LIM-only protein FHL2. Five proteins share the same structural organization and a high degree of sequence homology in this group: four and a half LIM domain protein (FHL) 1, FHL2, FHL3, FHL4, and activator of cAMP-responsive element (CRE) modulator (CREM) in testis (ACT). LIM domains are constituted by a conserved cysteine- and histidine-rich structure shaped in two repeated zinc fingers first identified in the proteins encoded by the Lin-11, Isl-1, and Mec-3 genes. The LIM domain has been shown to function as a protein-protein interaction domain, and has often been described in association with other functional protein motiFunctional Studies, such as homeobox and kinase domains. FHL2 seems to be a promiscuous coactivator because it modulates the activity of the androgen receptor, CRE-binding protein (CREB), and WT1, although some degree of specificity is present because it is unable to stimulate CREM- and Sp1-dependent transcription. FHL2 expression was originally described to be restricted to the heart but it is inducible in other cell types. FHL2 shows specific interaction with beta-catenin, which requires the intact structure of all four LIM domains of FHL2 and the N-terminus plus the first armadillo repeat region of beta-catenin. FHL2 is a muscle-specific repressor of LEF\/TCF target genes and promotes myogenic differentiation by interacting with beta-catenin. Monoclonal antibody F4B2-B11 recognizes the N-terminal Zn-Finger motif, it does not crossreact in Western Blotting with the FHL1 and FHL3 proteins. The F4B2-B11 antibody is cross reactive with mouse and rat FHL2.\u003c\/li\u003e\n\u003cli\u003eApplications: Frozen sections, Immunofluorescence , Paraffin sections , Western Blot\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614142914851,"sku":"HYBHM2136100UG","price":1086.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_8df918a0-71e7-4b9f-ba13-c838b49cc7ea.png?v=1753031592"},{"product_id":"fhl2-human-mab-f4b2-b11-20-ug","title":"FHL2, Human, mAb F4B2-B11, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614142947619,"sku":"HYBHM213620UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_396d47ec-4b07-4ffa-b038-ed72f60fe2c3.png?v=1753031595"},{"product_id":"ficolin-1-human-mab-7g1","title":"Ficolin-1, Human, mAb 7G1","description":"\u003cul\u003e\n\u003cli\u003eThe monoclonal antibody 7G1 recognizes human M-ficolin, also known as ficolin-1. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: M-Ficolin, L- Ficolin (Ficolin-2), and H-Ficolin (Ficolin-3). M-Ficolin, is mainly expressed by- monocytes, granulocytes and- lung cells and is present locally in areas of inflammation. However, it was recently also found in serum suggesting that M-Ficolin also has a role in systemic immunity like L- and H-Ficolin. Functional analysis of M-Ficolin has demonstrated that it's ligand is sialic acid present on bacteria since binding was abolished by prior treatment of the bacteria with sialidase. Furthermore, it was shown that M-ficolin facilitates the uptake of E. coli- by a leukemic monocyte lymphoma cell line, suggesting that it functions as a phagocytic receptor on the surface of circulating monocytes. Low cord blood concentration of M-ficolin has been- associated with higher necrotizing enterocolitis-associated fatality and two identified SNPs in the M-ficolin gene are associated with the development of rheumatoid arthritis. The monoclonal antibody 7G1 is suitable for use in immunoassays and western blotting. -\u003c\/li\u003e\n\u003cli\u003eApplications: Flow Cytometry , Immunoassays , Western Blot\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614149009699,"sku":"HYBHM2196100UG","price":990.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_45281da0-2968-4d84-a9d7-e5d5287dc0bc.png?v=1753031798"},{"product_id":"ficolin-1-human-mab-7g1-20-ug","title":"Ficolin-1, Human, mAb 7G1, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614149042467,"sku":"HYBHM219620UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_dcf72ad4-1893-4c39-a562-fe53dfed06a9.png?v=1753031801"},{"product_id":"factor-ba-human-mab-d22-3","title":"Factor Ba, Human, mAb D22\/3","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614160314659,"sku":"HYBHM2379100UG","price":726.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_97a55a40-4f8d-45d1-bf63-615236450ba4.png?v=1753032154"},{"product_id":"factor-ba-human-mab-d22-3-20-ug","title":"Factor Ba, Human, mAb D22\/3, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614160347427,"sku":"HYBHM237920UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_b513684a-fbff-49aa-91f6-8e067975ace6.png?v=1753032157"}],"url":"https:\/\/chromspec.com\/collections\/14965-antibody-name-f.oembed?page=2","provider":"Chromatographic Specialties Inc.","version":"1.0","type":"link"}