{"title":"15007-Lipid A","description":"","products":[{"product_id":"lipid-a-mab-26-5","title":"Lipid A, mAb 26-5","description":"\u003cul\u003e\n\u003cli\u003eThe monoclonal antibody 26-5 recognizes lipid A. The lipid A domain of lipopolysaccharide (LPS) is aunique, glucosamine-based phospholipid that makes up the outer monolayer of the outer membrane ofmost gram-negative bacteria.Lipid A is responsible for the endotoxic activities of LPS, and a heteropolysaccharide. Theheteropolysaccharide generally consists of an oligosaccharide termed the core region. This core regionis in some bacterial families composed of repeating oligosaccharide units, the so-called O chain. Thelipid A moiety of LPS is detected by the TLR4\/MD2 receptor of the mammalian innate immune system.Picomolar levels of lipid A induce macrophages to synthesize potent mediators of inflammation, such asTNF-α and IL-1β. Furthermore, lipid A activates the production of costimulatory molecules required foradaptive immunity and stimulates tissue factor production in mononuclear and endothelial cells. Allthese events are desirable for clearing local infections.\u003c\/li\u003e\n\u003cli\u003eApplications: Immunoassays\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614166966563,"sku":"HYBHM6009100UG","price":893.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_5faacae3-5d3a-48aa-b175-29b033036e8d.png?v=1753032427"},{"product_id":"lipid-a-mab-26-5-20-ug","title":"Lipid A, mAb 26-5, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614166999331,"sku":"HYBHM600920UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_a3f3c2ab-f6f3-4e8e-90d3-9e17146aebd6.png?v=1753032430"}],"url":"https:\/\/chromspec.com\/collections\/15007-lipid-a.oembed","provider":"Chromatographic Specialties Inc.","version":"1.0","type":"link"}