{"title":"15034-IL-1RII","description":"","products":[{"product_id":"il-1rii-human-pab-100-ug","title":"IL-1RII, Human, pAb, 100 µg","description":"\u003cul\u003e\n\u003cli\u003eThe antibody reacts specificly with human Interleukin (IL-1)RII. The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1RI and IL-1RII) and the IL-1 receptor accessory protein. The IL-1RII is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signalling molecule which functions by capturing IL-1 and preventing it from interacting with the signalling IL-1RI. The decoy IL-1RII can after binding to IL-1 also recruit the IL-1 receptor accessory protein and thus inhibit by coreceptor competition. Further a soluble form of IL-1RII exists which is shed, a process in which matrix metalloproteases have been found to play a role, by various cells including monocytes, polymorphonuclear cells, B cells and fibroblasts.\u003c\/li\u003e\n\u003cli\u003eApplications: Immunoassays\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614169325859,"sku":"HYBHP9007100UG","price":726.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_3d28ed18-2609-48ca-b456-8e473cec1d0c.png?v=1753032502"},{"product_id":"il-1rii-human-pab","title":"IL-1RII, Human, pAb","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614169358627,"sku":"HYBHP900720UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_470eaebc-8efd-481e-93b4-72c0e15df58b.png?v=1753032505"}],"url":"https:\/\/chromspec.com\/collections\/15034-il-1rii.oembed","provider":"Chromatographic Specialties Inc.","version":"1.0","type":"link"}