{"title":"15114-C5aR","description":"","products":[{"product_id":"c5ar-human-mab-s5-1","title":"C5aR, Human, mAb S5\/1","description":"\u003cul\u003e\u003cli\u003eThe monoclonal antibody S5\/1 recognizes the human receptor for C5a (CD88). The C5a receptor- is a seven transmembrane GTP-binding-protein-coupled receptor of 45kDa which binds with high affinity to human anaphylatoxin C5a. Upon C5a binding- G-protein-dependent cellular- responses are initiated such as increased intracellular Ca2+, granule fusion with the cell membrane, enzyme release and oxidative burst suggesting that C5aR is an important mediator of inflammation. The C5a receptor is expressed on a broad range of cell types, including- neutrophils, monocytes\/macrophages, dendritic cells, astrocytes and microglia.\u003c\/li\u003e\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139834659,"sku":"HYBHM2094100UG","price":893.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_b924c383-8af7-4319-baa2-76ca6a7cd388.png?v=1753031470"},{"product_id":"c5ar-human-mab-s5-1-20-ug","title":"C5aR, Human, mAb S5\/1, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139867427,"sku":"HYBHM209420UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_4ba083ec-8945-44fb-b362-a39ca01267ef.png?v=1753031473"},{"product_id":"c5ar-human-mab-w17-1","title":"C5aR, Human, mAb W17\/1","description":"\u003cul\u003e\n\u003cli\u003eThe human anaphylatoxin C5a is a 74-residu glycopolypeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a could be demonstrated, rendering this molecule an important mediator of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP-binding-protein-coupled receptor that belongs to the rhodopsin supergene family. The C5a receptor is approximately 45 kDa.\u003c\/li\u003e\n\u003cli\u003eApplications: Frozen sections, Flow Cytometry , Parrafin Sections\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139900195,"sku":"HYBHM2095100UG","price":893.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_282eae84-46a8-468a-81bc-5c9d7878fbc6.png?v=1753031332"},{"product_id":"c5ar-human-mab-w17-1-20-ug","title":"C5aR, Human, mAb W17\/1, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614139932963,"sku":"HYBHM209520UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_73dfb561-3081-4642-bec0-ba1d613370c7.png?v=1753031335"}],"url":"https:\/\/chromspec.com\/collections\/15114-c5ar.oembed","provider":"Chromatographic Specialties Inc.","version":"1.0","type":"link"}