{"title":"15131-CD11b","description":"","products":[{"product_id":"cd11b-human-mab-bear-1","title":"CD11b, Human, mAb Bear-1","description":"\u003cul\u003e\n\u003cli\u003eCD11b is an alpha chain integrin that is expressed as heterodimer noncovalently associated with CD18. CD11b is also designated as CR3, Mac-1, Mo-1 in integrin alphaM subunit and has a molecular weight of 165-170 kDa. The protein mediates PMN and monocytes adherence to endothelium and subsequently PMN extravasation to sites of inflammation. CD11b\/CD18 interacts with both matrix and cell surface proteins including the complement component iC3b, extracellular matrix proteins and the third extracellular domain of CD54. CD11b is expressed on human NK-cells, monocytes, granulocytes, T-cells, B-cells and dendritic cells. After activation the expression is upregulated. Bear-1 reacts with the CD11b alpha chain of the CD11b\/CD18 (p165, 95) integrin heterodimer complex.\u003c\/li\u003e\n\u003cli\u003eApplications: Frozen sections, Flow Cytometry , Immunoprecipitation\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614142325027,"sku":"HYBHM2125100UG","price":726.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_636cd156-105d-49c5-942d-9b463b51d481.png?v=1753031536"},{"product_id":"cd11b-human-mab-bear-1-20-ug","title":"CD11b, Human, mAb Bear-1, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614142357795,"sku":"HYBHM212520UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_9c99cfd8-ef2b-4b11-ad7b-db1b7c1b855c.png?v=1753031539"}],"url":"https:\/\/chromspec.com\/collections\/15131-cd11b.oembed","provider":"Chromatographic Specialties Inc.","version":"1.0","type":"link"}