{"title":"15515-Antibody Name N","description":"","products":[{"product_id":"neutrophils-mouse-mab-nimp-r14","title":"Neutrophils, Mouse, mAb NIMP-R14","description":"\u003cul\u003e\n\u003cli\u003eThe monoclonal antibody NIMP-R14 is highly specific for murine Ly-6G and Ly-6C. The Ly-6G\/-6C locus encodes a family of Ly-6 proteins including Ly-6G and Ly-6C. Ly-6 antigens have a molecular weight between 15,000 and 18,000. Ly6G is together with Ly6c a component of the myeloid differentiation antigen Gr-1. Ly6G a GPI-anchored protein and is a good marker of peripheral neutrophils. Although predominantly presents on neutrophils, it is also expressed on a subset of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells. Ly6C is a monocyte\/macrophage and endothelial cell differentiation antigen regulated by interferon gamma, and may play a role in the development and maturation of lymphocytes. It is expressed on bone marrow cells, monocytes\/macrophages, neutrophils, endothelial cells, and T cell subsets. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. However, the physiological role of Ly6G alone remains still unclear. The monoclonal antibody NIMP-R14 has been successfully used to stain polymorphonuclear (PMN) cells and monocytes for fluorescent activated cell sorting and in frozen and paraffin sections. Treatment with antibodies in vivo leads to neutropenia and has inhibitory effect on local immune responses.Furthermore, it has been shown to be useful for depletion of neutrophils in mice. It depletes neutrophils as soon as 6 hours after injection and up to 6 days.\u003c\/li\u003e\n\u003cli\u003eApplications: Frozen sections, Flow Cytometry , Functional Studies , Immunoassays , Paraffin Sections\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614119387427,"sku":"HYBHM1039100UG","price":645.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_18e1d727-8782-4873-84ad-0e49a061c2ea.png?v=1753030592"},{"product_id":"neutrophils-mouse-mab-nimp-r14-10-mg","title":"Neutrophils, Mouse, mAb NIMP-R14, 10 mg","description":null,"brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614119420195,"sku":"HYBHM103910MG","price":14815.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_e416241d-b868-40ab-bee8-0d5360bf30f4.png?v=1753030596"},{"product_id":"neutrophils-mouse-mab-nimp-r14-1-mg","title":"Neutrophils, Mouse, mAb NIMP-R14, 1 mg","description":null,"brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614119452963,"sku":"HYBHM10391MG","price":2965.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_08852cc9-a828-4e44-a850-acec4284d9d9.png?v=1753030599"},{"product_id":"neutrophils-mouse-mab-nimp-r14-20-ug","title":"Neutrophils, Mouse, mAb NIMP-R14, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614119485731,"sku":"HYBHM103920UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_36503ccc-22b2-4720-86de-77aab057294d.png?v=1753030602"},{"product_id":"neutrophils-mouse-mab-nimp-r14-500-ug","title":"Neutrophils, Mouse, mAb NIMP-R14, 500 µg","description":null,"brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614119518499,"sku":"HYBHM1039500UG","price":2080.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_db5c69d3-877b-4561-8d6c-b2e64cc72fa6.png?v=1753030606"},{"product_id":"neutrophils-mouse-mab-nimp-r14-5-mg","title":"Neutrophils, Mouse, mAb NIMP-R14, 5 mg","description":null,"brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614119551267,"sku":"HYBHM10395MG","price":11107.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_d043def8-d946-4cbf-b272-48aa7f5f06e8.png?v=1753030609"},{"product_id":"nectin-2-mouse-mab-502-57","title":"Nectin-2, Mouse, mAb 502-57","description":"\u003cul\u003e\n\u003cli\u003eNectin (originally isolated as poliovirus receptor-related protein (PRR)) is a cell-cell adhesion molecule of the immunoglobulin supergene family. Nectin is colocalized with afadin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. The nectin family consist of nectin-1, nectin-2 and nectin-3. Nectin-2 also known as PRR2 or CD112 is a plasma membrane adhesion molecule localized at adherens junctions which is widely expressed in various cell lines including neuronal, endothelial, epithelial and hematopoietic cells. Next to its role in adherens junctions it functions as alphaherpus virus receptor and acts also as intercellular adhesion molecule and pseudorabies virus receptor. Disruption of mouse nectin-2 leads to infertility of male mice. Monoclonal antibody 502-57 has been raised against the extracellular domain of mouse nectin-2. The antibody cross reacts with human nectin-2.\u003c\/li\u003e\n\u003cli\u003eApplications: Frozen sections, Flow Cytometry , Immunoassays , Immunoprecipitation , Western Blot\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614122565923,"sku":"HYBHM1052100UG","price":990.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_26214668-6787-43df-9068-f90626cfed8d.png?v=1753030708"},{"product_id":"nectin-2-mouse-mab-502-57-20-ug","title":"Nectin-2, Mouse, mAb 502-57, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614122598691,"sku":"HYBHM105220UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_47231f1f-558c-4a58-bae8-0727b6a20e83.png?v=1753030711"},{"product_id":"nectin-3-mouse-mab-103-a1","title":"Nectin-3, Mouse, mAb 103-A1","description":"\u003cul\u003e\u003cli\u003eThe monoclonal antibody 103-A1 recognizes mouse nectin-3. Nectin-3 is a 83 kDa type I\u003c\/li\u003e\u003c\/ul\u003e","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614122696995,"sku":"HYBHM1053100UG","price":893.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_4aab0fe6-eba3-47da-a364-667d461ea173.png?v=1753030718"},{"product_id":"nectin-3-mouse-mab-103-a1-20-ug","title":"Nectin-3, Mouse, mAb 103-A1, 20 µg","description":" ","brand":"Hycult Biotech","offers":[{"title":"Default Title","offer_id":53614122729763,"sku":"HYBHM105320UG","price":265.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Hycult_20800x800_20100dpi_190935e2-b550-4344-8fc0-74c315682350.png?v=1753030721"}],"url":"https:\/\/chromspec.com\/collections\/15515-antibody-name-n.oembed","provider":"Chromatographic Specialties Inc.","version":"1.0","type":"link"}