**Nucleosome, Recombinant Human, H3K4me3 dNuc, Biotinylated, Ship Product on Dry Ice, 20 µg

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EP16031620
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Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2B-O60814; H3.2-Q71DI3*; H4-P62805) wrapped by 147 base pairs of 601 positioning sequence DNA. Histone H3 (created by a proprietary semi-synthetic method) contains trimethyl-lysine at position 4. The nucleosome is the basic subunit of chromatin. The 147 bp 601 sequence, identified by Lowary and Widom [1], has high affinity for histone octamers and is useful for nucleosome assembly. The DNA contains a 5’ biotin-TEG group. *H3K4me3 has a Cys to Ala substitution at position 110.

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20UG
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DRYICE - Product Ships with Dry Ice