**Nucleosome, Recombinant Human, H2AXS139phos dNuc, Biotinylated, Ship Product on Dry Ice

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EP160366
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Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2AX, H2B, H3 and H4; accession numbers: H2AX-P16104; H2B-O60814; H3.1-P68431; H4-P62805) wrapped by 147 base pairs of 601 positioning sequence DNA. Histone H2AX (created by a proprietary synthetic method) contains phosphorylated-serine at position 139. The nucleosome is the basic subunit of chromatin. The 601 sequence, identified by Lowary and Widom, is a 147-base pair sequence that has high affinity for histone octamers and is useful for nucleosome assembly and contains a 5' biotin-TEG group.

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50UG
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DRYICE - Product Ships with Dry Ice