Ficolin-3, Human, mAb 4H5

SKU:
HYBHM2089100UG
Pending approval

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Description

Product Details

  • The monoclonal antibody 4H5 recognizes human Ficolin-3, also known as H-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation.
  • Ficolin-3 (also Hakata antigen, H-ficolin or ficolin H) is produced by the liver and by the lung. Ficolin-3 is associated with three types of MASPs and sMAP, this complex activates C4, C2 and C3 in the fluid phase.
  • Applications: Immunoprecipitation
Additional Information
Sales Unit:
100UG
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ROOMTEMP - Ships at Room Temperature