e-Chronicle – June 2025
Your Chromatography Update – Liquid Chromatography

In this month's e-Chronicle Newsletter, we've featured a variety of LC-related topics, including new products, green initiatives, instrumentation, technical resources, and more!

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CSI is now using the 12 point SIGNIFICANCE mnemonic to assess greener analytical chemistry technology. 

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NEW PRODUCTS
Restek – Raptor C8 Columns

A Restek column offering a shorter alkyl chain to provide less hydrophobic retention over a traditional C18 phase.
Like Raptor C18, this general-purpose C8 is suitable for a wide range of compounds from acidic through slightly basic.

• 2.7 µm SPP core-shell silica.
• Similar selectivity to C18 with less retention of nonpolar analytes for faster analysis times.

Green Chemistry:
enerate as little waste as possible and treat it properly.
liminate or replace toxic reagents.

   

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Pickering Laboratories – Artificial Gastric and Intestinal Fluids

Pickering Laboratories Artificial Body Fluid Products are made to official product testing specifications from official
standards organizations for product testing and research applications. Check out the newest additions to their
product line – digestive fluids.

• For dissolution and pharmacokinetic studies of drug formulations.
• Also used to study the safety of products that risk accidental ingestion.
• Prepared according to USP specifications.
• Can be ordered complete or with pre-weighed dry enzymes to add at time of use.
• Excellent batch reproducibility and precise matching of official formulations.

   

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LGC – Microplastic Reference Materials

Microplastic contamination is rising in the environment, food, pharmaceuticals, and humans due to widespread
plastic and microplastic use.

LGC has released reference materials for advancing microplastic understanding and developing testing methods
and regulations.

• Pure polymers with specific particle size distribution.
• Target testing to identify specific microplastic types in real samples.
• Measure effect of specific plastics without interference from other materials.
• Include the most common microplastics.
• Certified to ISO/IEC 17025 and ISO 17034.

   

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Featured Product
Axcend – Focus LC^®

Axcend Focus is a fully functional LC in a single, integrated box. It provides 600 bar UHPLC performance with a small
footprint and low energy consumption. 

• Do More With Less: Delivers reliable, repeatable data – but uses up to 1000x less solvent and significantly less energy using
  simplified capillary technology.
• Proven ROI: Slashes solvent use, waste, and energy costs, generating significant operational savings and pays for itself in as little as 2 years.
• Flexible & Future-Ready: Unlocks new workflows, new use cases, and new opportunities. Designed to scale with you – today and tomorrow.
• Safer & More Sustainable: Requires fewer solvent changes, less hazardous waste, and lower fire risk. 
• Small Footprint:  8"H x 9"W x 13"D

Green Chemistry:
enerate as little waste as possible and treat it properly.
ever waste energy.
mplement automation and miniaturization of methods.

   

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Technical Tip
Easy HPLC Solvent Savings

You can cut your HPLC solvent use dramatically by scaling back on the diameter or particle size and length of your column.

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Junior Scientist
New This Month...

CSI launches a series of scientific experiments or projects for pre-school through high school students.
These articles will appear in our June, July and February e-Chronicles, to give ideas for the summer holidays
and March break.

This month, courtesy of the ACS:

Glacier Science:

• Trapped gas analysis from glaciers.
• Where does glacial melt water go in lakes and oceans?
• How does water temperature and movement affect glaciers melting?