{"product_id":"azdye™-555-picolyl-azide-5-mg","title":"AZDye™ 555 Picolyl Azide - 5 mg","description":"\u003cp class=\"richp\"\u003eAZDye™ 555 Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boost the efficiency of the CuAAC reaction, resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides, was reported (see Selected References).\u003c\/p\u003e\u003cp class=\"richp\"\u003eIn addition, the use picolyl azides instead of conventional azides allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling, significantly improving biocompatibility of CuAAC labeling protocol.\u003c\/p\u003e\u003cp class=\"richp\"\u003eIn summary, the introduction of a copper-chelating motif into azide probe leads to a substantial increase in the sensitivity and reduced cell toxicity of CuAAC detection alkyne-tagged biomolecules. This will be of special value for the detection of low abundance targets or living system imaging.\u003c\/p\u003e\u003cp class=\"richp\"\u003eAZDye™ 555 Picolyl Azide is a water-soluble, bright orange-fluorescent dye with excitation ideally suited for the 532 nm or 555 nm laser lines and visualized with TRITC (tetramethylrhodamine) filter sets. AZDye™ 555 is structurally similar to Alexa Fluor® 555, and spectrally is almost identical to Cy3 Dye, Alexa Fluor® 555, CF® 555 Dye, or any other Cyanine3 based fluorescent dyes.\u003c\/p\u003e\u003ctable style=\"width: 1729px; border-collapse: collapse;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"width: 689.594px; text-align: left; white-space: nowrap;\"\u003eCAS Number\u003c\/th\u003e\n\u003ctd\u003eN\/A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eMolecular Weight\u003c\/th\u003e\n\u003ctd\u003e1338.8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eAppearance\u003c\/th\u003e\n\u003ctd\u003eRed Solid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eExtinction Coefficient\u003c\/th\u003e\n\u003ctd\u003e155,000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003ePurity\u003c\/th\u003e\n\u003ctd\u003e\u0026gt;95% (HPLC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eUnit Size\u003c\/th\u003e\n\u003ctd\u003e1 mg, 5 mg, 25 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eSolubility\u003c\/th\u003e\n\u003ctd\u003eWater, DMSO, DMF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eStorage Instructions\u003c\/th\u003e\n\u003ctd\u003e-20°C, Desiccate\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eSpectrally Similar Dyes\u003c\/th\u003e\n\u003ctd\u003eAlexa Fluor® 555, CF® 555, DyLight® 549, Cy3 Dye\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eLaser Line\u003c\/th\u003e\n\u003ctd\u003e532 nm or 555 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eExcitation\/Emission Maximum\u003c\/th\u003e\n\u003ctd\u003e555\/572 nm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eShipping Conditions\u003c\/th\u003e\n\u003ctd\u003eAmbient Temperature\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eShipping Instructions\u003c\/th\u003e\n\u003ctd\u003eAmbient Temperature\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"Vector Laboratories","offers":[{"title":"Default Title","offer_id":55904579223843,"sku":"VECTCCT1288R5","price":0.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Vector_CCT-1288R_azdye_555_picolyl_azide_2048x2048pxl_ee89bee7-b247-4c12-a749-36834e380ab7.jpg?v=1793598312","url":"https:\/\/chromspec.com\/products\/azdye%e2%84%a2-555-picolyl-azide-5-mg","provider":"Chromatographic Specialties Inc.","version":"1.0","type":"link"}