{"product_id":"pam-2-cas-1426293-61-9-50-mg","title":"***PAM-2, CAS # 1426293-61-9, 50 mg","description":"\u003cp class=\"richp\"\u003ePAM-2 is a potent, orally active, blood-brain barrier-penetrant selective positive allosteric modulator of α7nAChR (human α7nAChREC50: 39 μM, rat α7nAChREC50: 12 μM), exhibiting anti-allodynic and anti-inflammatory properties. It shows selectivity for α9α10nAChR (IC50= 174 μM) and CaV2.2 channel (IC50= 89 μM). By enhancing α7nAChR activity, PAM-2 alleviates neuropathic pain induced by Streptozotocin (STZ) and Oxaliplatin in mice. PAM-2 is useful in the study of neuropathic pain.\u003c\/p\u003e\u003ctable style=\"width: 1729px; border-collapse: collapse;\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"width: 689.594px; text-align: left; white-space: nowrap;\"\u003eCAS Number\u003c\/th\u003e\n\u003ctd\u003e1426293-61-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eMolecular Weight\u003c\/th\u003e\n\u003ctd\u003e227.2585\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eMolecular Formula\u003c\/th\u003e\n\u003ctd\u003eC14H13NO2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eTarget\u003c\/th\u003e\n\u003ctd\u003eAChR, Calcium Channel\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eStorage Temperature\u003c\/th\u003e\n\u003ctd\u003e-20°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eExpiration Date\u003c\/th\u003e\n\u003ctd\u003e12 Months from Date of Receipt\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth scope=\"row\" style=\"text-align: left; white-space: nowrap;\"\u003eDisclaimer\u003c\/th\u003e\n\u003ctd\u003eFor Research Use Only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"Biorbyt","offers":[{"title":"Default Title","offer_id":56035682943267,"sku":"ORB321153850MG","price":0.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/3870\/8003\/files\/Biorbyt_small_molecules_and_tools_2048x2048_0652917e-8578-4e08-a6b7-9cc965197cb1.jpg?v=1794289495","url":"https:\/\/chromspec.com\/products\/pam-2-cas-1426293-61-9-50-mg","provider":"Chromatographic Specialties Inc.","version":"1.0","type":"link"}