*3.0 N HCl in n-Butanol, CAS # 7647-01-0, 100 mL

SKU:
RT201009
Pending approval

Log in for pricing

(No reviews yet)
Gift wrapping:
Options available
Current Stock:
Adding to cart… The item has been added
Description
3N HCl in n-Butanol is required for newborn screening for metabolic disorders. Neonatal screening, which has become a standard procedure in many countries, measuring amino acids and acylcarnitines from a single drop of blood. Blood concentration of one or several of these compounds is either abnormally high or low in a variety of metabolic diorders in newborns. Dervivatization with 3N HCl in n-Butanol ensures butylation of the carboxyl acid group of the analyte and formation of butyl ester, which forces ionization or makes charging of the analytes more efficient. Although direct analysis of extracted acycarnitine without derivatization is possible, according to different reports, butylesterification is superior with regards to sensitivity and specificity. 3N HCl in n-Butanol from Regis Technologies is manufactured under cGMP protocols to assure the highest quality and lot to lot consistency for this reagent. Each lot is tested by tandem mass spectrometry to ensure absence of contaminants which may interfere with analysis.
Additional Information
Sales Unit:
100ML
Additional_Shipping:
TDG - Regulated for Transport