Eliminate poorly swept volume and improves peak symmetry
Higher corrosion resistance
Various porosities and dimensions available
In terms of biocompatibility, the frit is the critical spot for contributing metal ions to the mobile phase and for interaction with protein samples.
VICI Jour PEEK-encased frits with 1/5" or 1/4" OD ring are intended for HPLC columns with IDs of 3.2 and 4.6 mm. With the frit surrounded by a PEEK ring, the actual porous surface is reduced to the column ID.
The compressed PEEK ring forms a seal between the bottom of the fitting and the column end, preventing the mobile phase and the sample from entering the previously accessible poorly swept areas.