2024 Sep 1st

MJS BioLynx e-Lynx - September 2024

MJS BioLynx Life Science Updates — New Products, Promotions, Announcements and more. …                   


MJS BioLynx Well Being

Invite a Lab Mate to Join Our e-Lynx Newsletter - and We'll Donate $5 Towards Our "Charity of the Month" Campaign

Our “Charity of the Month” for September is the  Terry Fox Run.

The annual Terry Fox Run has become a fall tradition in Canada, with more than 600 communities, big and small, urban and rural, fundraising for cancer research. This year, you can register and participate on Sunday, September 15!

The money you raise each year in Terry’s name supports world-class cancer research at the Terry Fox Research Institute (TFRI) and in laboratories, clinics, centres, and hospitals around the country and beyond.

Send this  sign-up link to your lab mate and we’ll donate $5 when we receive their completed sign-up.


NEW PRODUCTS

EpiCypher – CUTANA™ Uncharged 6xHis-pAG-Tn5 for CUT&Tag

Products in EpiCypher’s IDEA Toolbox (Innovation and Discovery of Epigenetic Applications) offer access to reagents without known or fully defined uses, enabling researchers to explore cutting-edge applications.

They have recently released CUTANA™ Uncharged 6xHis-pAG-Tn5 for CUT&Tag.

This is a fusion of proteins A and G to E.coli transposase (Tn5), the key enzyme for CUT&Tag [1]. The fusion protein contains a polyhistidine tag (6xHis) to enable applications that require affinity purification steps.

For more information about the applications and Validation data of pAG-Tn5, click on the “learn more” button below.


Background References:
[1] Kaya-Okur et al. Nat. Commun. (2019). PMID: 31036827
[2] Meers et al. Nat. Biotechnol. (2023). PMID: 36316484
[3] Gopalan et al. Mol. Cell (2021). PMID: 34637755

   



USA Scientific – Vortex Mixer - Practical Elegance

A compact mixer and vortexer in one! Touch a tube to the standard adapter for quick vortexing or set specific speed and duration to mix plates and tubes.

The Vortex Mixer is ideally suited for assay protocols that require gentle mixing up to resuspensions that require vigorous vortexing.

  • 2-in-1 Convenience – Mix and vortex in one compact device.
  • Precise Speed and Duration Control – Use the digital presets for quick vortexing or customize for precise mixing.
  • Glove Compatible Touchscreen – Keep gloves on while programming.
  • Quick Touch Mode – Press the tube to the standard attachment for quick gentle mixing to vigorous vortexing.

For a limited time, purchase the Vortex Mixer and receive the tube adapter and microplate adapters included.

   


FEATURED PRODUCTS

Vector Laboratories – VECTASHIELD® Antifade Mounting Media & TrueVIEW® Autofluorescence Quenching Kits

If you love the Vector Laboratories’  VECTASHIELD Antifade Mounting Media - The MOST widely referenced antifade mounting media, then you may also love the TrueVIEW Autofluorescence Quenching Kits.
These kits provide a novel way to remove unwanted fluorescence in tissue sections due to aldehyde fixation, red blood cells, and structural elements such as collagen and elastin.

TrueVIEW Quenching reagent is a unique approach to diminish unwanted autofluorescence from non-lipofuscin sources, that retains the specific fluorescent antigen staining. The quenching action of the kit reagents therefore, provides the investigator with a clear, unambiguous, “true view” visualization of the intended target.

You may also like the  VectaPlex™ Antibody Removal Kit. This ready-to-use kit is designed to remove antibodies and other non-covalently bound detection reagents from formalin-fixed paraffin-embedded (FFPE) tissue sections in immunofluorescence or tyramide signal amplification staining workflows.

Take advantage of our Vector Promotion below and receive 50% off of a product you’ve never tried before!

 VECTASHIELD - Antifade Mounting Media

 TrueVIEW - Autofluorescence Quenching Kits

 VectaPlex Antibody - Removal System


Associates of Cape Cod, Inc. – PyroSmart NextGen® Recombinant Cascade Reagent (rCR)ACC Logo

News Flash! U.S. Pharmacopeia (USP) Microbiology Expert Committee to permit the use of non-animal-derived reagents for endotoxin testing.

With this announcement, pharmaceutical and medical device manufacturers can consider with confidence, integrating this new recombinant technology platform into their quality assurance processes.

Now's the time to find out how easy transitioning to PyroSmart NextGen® is.

  • No Animal Content – Horseshoe Crab Blood Free
  • Same Cascade, Instrument & Preparation Steps
  • No Cross Reactivity With 1,3-ß-D-Glucan

PyroSmart NextGen® can be used for a wide variety of endotoxin tests, ranging from standard water testing to samples requiring high sensitivity, such as intrathecal products and those requiring high dilutions to overcome interference.

  


Mirus Bio – Discovery Research

Spend less time searching for a transfection reagent and more time moving your innovations forward.

Mirus Bio offer a range of effective transfection solutions and tools for a comprehensive set of cell lines. These solutions are intentionally designed to be gentle on cells and maximize cell delivery while using a simplified, straightforward protocol.

Discovery Research Applications

CRISPR/Cas Genome Editing
Stem Cell Transfection
RNAi Gene Silencing
mRNA and Viral RNA Transfection
Stable Cell Line Generation
Low Toxicity Transfection
Co-Transfection
Electroporation

Our Top Selling Transfection Reagent – TransIT®-LT1 Transfection Reagent

  • Broad Spectrum DNA Delivery – Utilize one transfection reagent and protocol for a variety of cells
  • High-Efficiency Delivery – Achieve expression in a large population of cells for experimental success
  • Deliver Single or Multiple Plasmids – Suitable for applications such as virus production
  • Request a Sample today!

TransIT®-LT1 Full Transfection Protocol (PDF)

      

We’re here to help you find the right Transfection Reagent for your research – Canadians helping Canadians.


ANNOUNCEMENTS

BioEcho – Webinar: The Adventures of RNA: A Fun Journey Through Purification

September 4, 2024 – 10:00AM (EST)

Presented by: Thomas Winkelmüller, PhD Sales Manager, BioEcho Life Sciences

Learning Objectives:

  • Understand the complexity of RNA extraction and be able to address its unique challenges.
  • Learn about the benefits of single-step purification when working with RNA.
  • Join a unique opportunity to learn about RNA purification in a fun and visual way.


MJS BioLynx – Go Green: Embracing a Greener Future

At MJS BioLynx, we are proud to represent many suppliers that are doing their part in reducing lab waste, without compromising quality. We offer a variety of products that may help you achieve your sustainability goals in your lab.

  • Labware and Equipment
  • Cell Biology
  • Molecular Biology
  • Microbiology and Endotoxin Testing


COME MEET US!

MJS BioLynx – September 2024 Shows

MJS BioLynx will be attending the following shows. Come and say hello and find out how our products can help you with some of your research challenges.


PROMOTIONS

Vector Laboratories – Buy 1 and Get a 2nd Product You Haven't Tried Before at 50% OFF


USA Scientific – Get 10% OFF Selected ErgoOne® Set, plus a free angled Pipette Stand and bag of Seal-Rite Tubes

   


NEST Biotechnology – Get a FREE Vintage CSI/BioLynx Jacket When You Accumulate $400 of NEST Labware

       


EpiCypher – New and Improved CUTANA™ CUT&Tag Kit – 20% OFF

   


TECHNICAL REPORTS

Revolutionizing Epigenomics with Single-cell CUT&Tag

Single-cell epigenomics has transformed our understanding of cellular diversity and gene regulation. By analyzing individual cells, researchers can uncover the intricate mechanisms driving cellular states and how these processes go awry in disease.

Explore New Genomic Applications with Multiomic CUT&Tag

Multiomic studies, which involve the integration of DNA, RNA, and protein “omics” datasets from a single cell or sample type, are helping researchers understand complex biological processes in development and disease.


PeptiGel vs. Collagen

When discussing 3D Cell Culture, researchers and scientists talk about collagen, a popular matrix material. Collagen does have limitations as a scaffold though, in a similar way to many other natural scaffold materials, which is one of the reasons why Cell Guidance Systems is offering a fully synthetic alternative – PeptiGels®.

Thank You!

The MJS BioLynx Team