EXP® Guard Columns - LC Column Protection for Extreme Pressure

Move to a Higher Standard of Ultra High Pressure Liquid Chromatography (UHPLC) Guard Hardware

Optimize Technologies’ EXP® Guard Columns feature innovations that significantly accelerate challenging UHPLC applications and reduce costly instrument downtime.

  • Ultra-low internal swept volume
  • Excellent protection with negligible impact on analyte retention and peak shape
  • Hand-tight cartridge changeover for use to 20,000+ psi (1,400+ bar)
  • Elegant design for easy installation in crowded instrument compartments
  • Direct connect and inline housing options are available

Optimize Technologies’ commitment to exceeding industry standards yields an entire EXP® product family conservatively rated to 20,000+ psi (1,400+ bar), including fittings, filters, and packed-bed products which offer unparalleled convenience and ease of use.  This advanced system is the first design to provide reusable hand-tight connections and hand-tight cartridge replacements for UHPLC.

Overall length:  2 1/4” (57mm)
Installed length (from inlet of analytical column to inlet of guard holder):  ~ 2” (50mm)

The EXP product line, as well as virtually all Optimize products, are proudly designed and manufactured by Optimize in Oregon.



Restek Columns Specific EXP® Guards
Column-Specific EXP Guard Column Cartridges are available for Restek Raptor™, Restek Force™, and YMC Triart Columns.  Contact us for help finding the best columns and guards for your specific needs.

YMC Triart 1.9µm
Triart UHPLC columns offer extreme chemical stability, allowing you to choose from a range of separation conditions to optimize selectivity without changing columns.  They are pH resistant from 1-12 (C8, C18 columns), stable to 70°C, and can be used with 0-100% organic or aqueous solvents.  YMC uses EXP hardware to provide column protection without sacrificing performance.  

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Click here to order or request a quote.


Restek Force™ 1.8µm
Force UHPLC columns offer a traditional fully porous silica particle for UHPLC (and HPLC) separations. Restek uses EXP hardware for their Force UHPLC guard columns, giving you an exact chemistry match in an easy-to-use format.

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Click here to order or request a quote.


Restek Raptor™ Superficially Porous Particles
Restek uses EXP guard hardware for their UHPLC 1.8µm, 2.7µm and 5µm Raptor columns. EXP’s minimized internal volume preserves the narrow peaks required for fast separations on SPP columns. It also allows columns to run reliably from 400 to 1,400 bar so UHPLC owners can exploit the full capacity of Raptor to speed up their runs.

Click on the links below for more information on Raptor phases:

Click here to order or request a quote.


FREE Technical Support

Our friendly and knowledgeable Technical Support Team consists of experienced chromatographers who understand the challenges facing separation scientists. This is a free service for our customers; we will not charge for helping you with your chromatography questions.