SKU: CK070090Available Quantity : 0
Get all the advantages of reversed-phase (RP) and hydrophilic interaction liquid chromatography (HILIC) in one column with the Thermo Scientific™ Acclaim™ Mixed-Mode HILIC-1 column. The high-efficiency, silica-based, mixed-mode stationary phase consists of a hydrophobic alkyl chain with a diol group at the terminus. The hydrophobic moiety supplies reversed-phase retention and the terminal diol group facilitates hydrophilic interactions. This unique combination provides adjustable selectivity with unsurpassed resolution and peak symmetry for a variety of both polar and nonpolar molecules.
Separates Both Polar and Nonpolar Molecules with Selectivity Complementary to RP Columns
- Operates in both RP and HILIC modes
- Retains highly polar molecules
- Covers broader application range than conventional diol-based columns, including nonionic ethoxylated surfactants, drug metabolites, lipids, and polyethylene glycols (PEGs)
- Stable between pH 2.5 and 7.5
- Available in 3 and 5 μm particle sizes with an average pore diameter of 120 Å
