Activin A, Species: Mouse

Activin A is a member of the Transforming Growth Factor ? (TGF-?) family of proteins with a wide range of biological activities. Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I and type II serine/threonine protein kinases, to activate SMAD signaling and regulate diverse cellular functions, such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A is a homodimer comprised of two activin ? A chains. Mouse Activin A shares 100% amino acid sequence identity with human, rat, porcine, bovine, and feline Activin A proteins.