**CUTANA™ ATAC-seq Kit, 24 Reactions

The CUTANA™ ATAC-seq Kit provides validated reagents and a streamlined workflow for generating sequencing-ready ATAC-seq libraries from cells or isolated nuclei. ATAC-seq was first described by Buenrostro et al. as a rapid method for mapping accessible chromatin by direct in vitro transposition of sequencing adapters into native chromatin [1]. The assay enables genome-wide analysis of open chromatin and regulatory element activity from low nuclei inputs.

The CUTANA™ ATAC-seq Kit includes pre-charged CUTANA™ Tn5 Transposome for ATAC-seq and optimized buffers for robust, reproducible chromatin accessibility profiling. Built on the foundation of the Omni-ATAC protocol described by Corces et al. and detailed by Grandi et al. [2,3], which established the performance standards researchers have come to expect from ATAC-seq, the CUTANA™ ATAC-seq Kit reimagines the workflow with optimized reagents and streamlined assay conditions designed to deliver a fully validated, user-friendly experience. These improvements support higher library yields, improved signal-to-noise, and consistent generation of high-quality sequencing-ready libraries from cells or isolated nuclei.

Features & Benefits:

• Streamlined workflow from cells to sequencing-ready ATAC-seq libraries
• Includes pre-charged CUTANA™ Tn5 Transposome for ATAC-seq
• Built on proven Omni-ATAC workflow principles
• Optimized buffers and workflow conditions for robust, reproducible performance
• Pair with CUTANA™ Nextera-Compatible Primers for a cells-to-libraries experience