CUTANA™ DNA Purification Beads, 500 mL

CUTANA™ DNA Purification Beads harness Solid-Phase Reversible Immobilization (SPRI*) technology to deliver fast, high-yield DNA cleanup and precise size selection for NGS library preparation and other genomic workflows. Optimized PEG and salt concentrations drive efficient, reproducible binding of DNA to paramagnetic beads, ensuring exceptional recovery with minimal bias or carry-over contamination. The formulation matches the bead-to-sample ratio of popular alternativessuch as AMPure XP* and SPRIselect*, ensuring CUTANA™ DNA Purification Beads can serve as a drop-in replacement into manual or automated cleanup workflows without any protocol re-optimization.

Key Advantages

• Trusted method– SPRI chemistry researchers rely on for DNA cleanup
• NGS validated – proven performance in genomic workflows including CUT&RUN, CUT&Tag, and library preparation
• High recovery & purity– consistently recovers DNA across a wide range of fragments and input amounts
• Automation-compatible– suitable for manual or automated protocols using magnetic separation
• Drop-in AMPure XP* alternative– identical ratios for seamless replacement in SPRI-based cleanups
• Room-temperature stable– ready to use; no warmup period required

Validated Applications

• CUT&RUN
• CUT&Tag
• NGS Library Preparation & adapter dimer cleanup

Formulation:  Paramagnetic bead suspension

Binding Mechanism:  SPRI (PEG/NaCl)

Size-selection Range:  Tunable via 0.8X – 1.8X bead-to-sample ratio

Handling:  Mix well by vortexing before use to resuspend beads uniformly