Datura stramonium lectin (DSL), Unconjugated

Datura Stramonium Lectin (DSL), Unconjugated, 5 mg, contains two chains of 40 kDa and 46 kDa joined by disulfide bonds. This lectin is free of a reported 32 kDa contaminant protein. The carbohydrate binding site recognizes (beta-1,4) linked N-acetylglucosamine oligomers, preferring chitobiose or chitotriose over a single N-acetylglucosamine residue. This lectin binds well in the acidic pH range but its affinity decreases above pH 8.0. DSL also binds well to N-acetyllactosamine and oligomers containing repeating N-acetyllactosamine sequences. A branched pentasaccharide including two N-acetyllactosamine disaccharides linked to mannose (beta-1,6) and (beta-1,2) was reported to be the most potent inhibitor of agglutination. Inhibiting/Eluting Sugar: Chitin Hydrolysate.