DyLight 649 Lens Culinaris Agglutinin (LCA, LcH), Affinity Purified

Product Details

Lens Culinaris Agglutinin (LCA), DyLight 649, 1 mg. LCA recognizes sequences containing alpha-linked mannose residues but recognizes additional sugars as part of the receptor structure, giving it a narrower specificity than Con A. An alpha-linked fucose residue attached to the N-acetylchitobiose portion of the core oligosaccharide significantly enhances affinity. By exploiting this narrower specificity, glycoproteins and glycopeptides can be subfractionated with LCA after initial isolation with Con A. DyLight 649–labeled LCA has an appropriate number of fluorochromes bound to provide the optimum staining characteristics for this lectin. This conjugate is supplied essentially free of unconjugated fluorochromes. The recommended concentration range for use is 5–20 µg/ml. Excitation maximum: 655 nm; Emission maximum: 670 nm; Color: Far red.