Griffonia (Bandeiraea) simplicifolia lectin I (GSL I, BSL I), Biotinylated

Product Details

Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I, BSL I), Biotinylated, 2 mg, is a family of glycoproteins with molecular weights of approximately 114 kDa. There are two types of subunits, termed "A" and "B," with slightly different molecular weights. These subunits combine to form tetrameric structures, resulting in five isolectins. The "A"-rich lectin preferentially agglutinates blood group A erythrocytes and thus appears to be specific for alpha-N-acetylgalactosamine residues, while the "B"-rich lectin preferentially agglutinates blood group B cells and is specific for alpha-galactose residues. This product is a mixture of the five isolectins. GSL I has been reported to bind several glycoproteins, including laminin. Biotinylated GSL I has an appropriate number of biotins bound to provide the optimum staining characteristics for this lectin. This conjugate is supplied essentially free of unconjugated biotins and is preserved with sodium azide.