Griffonia Simplicifolia Lectin I (GSL I) isolectin B4, Unconjugated

Griffonia Simplicifolia Lectin I (GSL I) isolectin B4, Unconjugated, 1 mg. GSL I is a family of glycoproteins with molecular weights of approximately 114 kDa. There are two types of subunits, termed A and B, with slightly different molecular weights. These subunits combine to form tetrameric structures, resulting in five isolectins. The A-rich lectin preferentially agglutinates blood group A erythrocytes and thus appears to be specific for alpha-N-acetylgalactosamine residues, while the B-rich lectin preferentially agglutinates blood group B cells and is specific for alpha-galactose residues. GSL I has been reported to bind several glycoproteins including laminin. GSL I-B4 isolectin contains only the B subunits. It is a useful marker for endothelial cells from nonprimates, such as mouse, rat, rabbit, and goat, and as a marker for non-peptidergic unmyelinated primary afferent neurons. Inhibiting Sugar: 500 mM galactose or 100 mM raffinose.