***H3K27me3 Antibody, SNAP-Certified™ for CUT&RUN and CUT&Tag

Product Details

This H3K27me3 (histone H3 lysine 27 trimethyl) meets EpiCypher’s lot-specific SNAP-Certified™ criteria for specificity and efficient target enrichment in both CUT&RUN and CUT&Tag applications. This requires <20% cross-reactivity to related histone PTMs determined using the SNAP-CUTANA™ K-MetStat Panel of spike-in controls. High target efficiency is confirmed by consistent genomic enrichment at varying cell inputs: 500k and 50k cells in CUT&RUN; 100k and 10k cells in CUT&Tag. High efficiency antibodies display similar peak structures at representative loci and highly conserved genome-wide signal even at reduced cell numbers. H3K27me3 is associated with repressed genes and is anti-correlated with H3K4me3, a marker of active gene transcription enriched at transcription start sites.