This H3K4me1 antibody (histone H3 lysine 4 monomethyl) meets EpiCypher’s lot-specific SNAP-Certified™ criteria for specificity and efficient target enrichment in both CUT&RUN and CUT&Tag applications. This requires <20% cross-reactivity to related histone PTMs determined using the SNAP-CUTANA™ K-MetStat Panel of spike-in controls. High target efficiency is confirmed by consistent genomic enrichment at varying cell inputs: 500k and 50k cells in CUT&RUN; 100k and 10k cells in CUT&Tag. High efficiency antibodies display similar peak structures at representative loci and highly conserved genome-wide signal even at reduced cell numbers. H3K4me1 either flanks H3K4me3 at the transcription start site (TSS) or coincides with H3K4me3.
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