IL-32 α, Species: Human

Interleukin-32 ? (IL-32 ?) is one of six known splice variants of the IL-32 gene. IL-32 ? induces the macrophage production of inflammatory cytokines, such as interleukin-8 (IL-8), Tumor Necrosis Factor ? (TNF-?), and Macrophage Inflammatory Protein 2 (MIP-2). IL-32 ? expression is increased after the activation of T cells, Natural Killer (NK) cells, and interferon ?-treated epithelial cells.