IP-10, Species: Mouse, 25UG

Interferon ϒ-induced protein 10 (IP-10), also known as CXCL10, is a chemokine secreted by monocytes, endothelial cells and fibroblasts in response to interferon ? (IFN-?). IP-10 functions as a chemoattractant for activated T cells, monocytes, dendritic, and Natural Killer (NK) cells that express the G protein-coupled receptor CXCR3. IP-10 is an important factor in autoimmune diseases such as Hashimoto's thyroiditis, Graves' disease, and Type 1 diabetes mellitus.