MIF, Species: Mouse, 5UG

Migration Inhibitory Factor (MIF) is a pro-inflammatory lymphokine that functions during cell-mediated immmunity. MIF promotes fibroblast migration by inducing interleukin-1 (IL-1), interleukin-8 (IL-8), and matrix metalloproteinase (MMP) expression. In interferon-?-activated macrophages, MIF stimulates nitric oxide (NO) production and Tumor Necrosis Factor ? (TNF-?) secretion.