***PAM-2, CAS # 1426293-61-9, 10 mg

Name: ***PAM-2, CAS # 1426293-61-9, 10 mg
Brand: Biorbyt
SKU: ORB321153810MG
Availability: InStock

SKU: ORB321153810MG

Available Quantity : 0

PAM-2 is a potent, orally active, blood-brain barrier-penetrant selective positive allosteric modulator of α7nAChR (human α7nAChREC50: 39 μM, rat α7nAChREC50: 12 μM), exhibiting anti-allodynic and anti-inflammatory properties. It shows selectivity for α9α10nAChR (IC50= 174 μM) and CaV2.2 channel (IC50= 89 μM). By enhancing α7nAChR activity, PAM-2 alleviates neuropathic pain induced by Streptozotocin (STZ) and Oxaliplatin in mice. PAM-2 is useful in the study of neuropathic pain.

CAS Number	1426293-61-9
Molecular Weight	227.2585
Molecular Formula	C14H13NO2
Target	AChR, Calcium Channel
Storage Temperature	-20°C
Expiration Date	12 Months from Date of Receipt
Disclaimer	For Research Use Only