Retinoic Acid, 50 mg

Retinoid RAR agonist

• Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
• Function / Pharmacology: all−trans−Retinoic acid (ATRA; a metabolite of Vitamin A) is an endogenous ligand for the retinoic acid receptor (RAR). The binding of retinoic acid to the RAR and retinoid X (RXR) heterodimer causes conformation changes in RAR that affects the binding of other proteins that regulate the growth and differentiation of a variety of both normal and malignant cells.1 ATRA promotes differentiation of embryonic stem cells (ESCs) into a variety of cell types in vitro.2-4
• CAS#: 302-79-4
• Molecular Weight:  300.44
• Molecular Formula:  C20H28O2
• Solubility:  Soluble in DMSO (up to 8 mg/ml) or in Ethanol (up to 15 mg/ml).
• Supplied:  powder
• Storage as supplied:  20°C
• Alternate Names:   ATRA; Tretinoin
• Purity:  >98%