TGF-β3 (AF), Species: Mouse

Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-? isoforms (TGF-?1, -? 2, and -? 3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-?3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-?3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.