Vandetanib, 25 mg

Vandetanib is an antagonist of VEGFR and EGFR families. Specifically inhibits kinase activity of Flk-1. It is also an inhibitor of Flt-4. Vandetanib is not sensitive to PDGFR beta Flt1 Tie-2 and FGFR1 while almost has no activity against MEK CDK2 c-Kit erbB2 FAK PDK1 Akt and IGF-1R.