e-Chronicle Newsletter

CSI E-Chronicle - March 2018

The e-chronicle is a monthly publication from Chromatographic Specialties Inc. It showcases new products, suppliers, literature and news from across the chromatography industry.


  • New Products
    • UCT - Refine™ 96 Well Ultra-Filtration Plates
    • Knauer – Azura® SMB for Multi-column or Batch LC
  • Featured Product
    • LCTech - FREESTYLE™ Automated Sample Preparation
  • New Application Notes
    • Removal of Purple Pigmentation from Cannabis using QuEChERS Extraction, ChloroFiltr® dSPE Clean-up and LC-MS/MS
    • Simplify Your LC-MS/MS Methylmalonic Acid (MMA) Analysis without Derivatization
  • New Literature
    • Coming Soon – 2018 Cost Savings Brochure


UCT - Refine™ 96 Well Ultra-Filtration Plates

  • Processes 96 samples in less than 20 minutes
  • Can be used with a wide range of biological sample types, such as plasma and urine
  • Accommodates in-well urinary enzyme hydrolysis and can withstand high incubation temperatures
  • Provides additional clean-up and filtration for cannabis analysis

Various biological sample types commonly contain proteins that complicate downstream analysis if not effectively removed. The use of UCT’s all new Refine™ 96 Well Ultra- Filtration Plates allow for sample precipitation and filtration to occur simultaneously in the same plate providing a fast and easy-to-follow protocol in under 15 minutes.

The novel, hydrophobically treated, dual frit combo mitigates any leakage of the sample/organic solvent through the plate before the application of negative or positive pressure. This ensures adequate filtering rather than pelleting precipitated proteins, not only extending the lifetime of an analytical column, but also eliminating any sample transfer steps.


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Knauer – Azura® SMB for Multi-column or Batch LC

  • Modular system designed to separate biomolecules or small molecules
  • Upgrade kits allow other configurations to be implemented easily such as batch configuration or the addition of a column thermostat
  • The PurityChrom® MCC software provides an interactive visualization of the installed system, giving you the opportunity to keep track of all important parameters

The ability to add more modules to the system as needed (such as pumps, valves, or detectors) and control all different operating modes with the same software makes it easy to handle and avoids compatibility issues that might arise when using heterogeneous system environments and configurations. Training effort is also minimized with the AZURA solution.


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